Diet and lifestyle habits have a profound impact on the pathophysiology of many diseases.
Colorectal cancer (CRC) is the third most common cancer worldwide and its etiology is
strongly influenced by nutrition and high fat/high carbohydrate Western-style diet. Human
epidemiological and animal studies have shown that colonic cancer risk is also related to
faecal bile acid concentration. Abnormally high levels of bile acids (BA) trigger the colonic
mucosa with a plethora of detrimental effects such as DNA oxidative damage, inflammation …